history of NAFDAC; management structure; NAFDAC's mode of operation; problems of spurious substandard and falsely-labelled falsified counterfeit medicines; NAFDAC’s efforts in fighting counterfeit, substandard and fake medicines and food products; previous efforts; use of modem technologies; global challenges of counterfeit, substandard and fake products; global phenomenon of counterfeiting; historical background of counterfeiting; global trend of counterfeiting; counterfeiting in Africa; Nigerian perspective; causative factors; global threats of counterfeiting; anti-counterfeiting measures; new and innovative solutions.